Diet Plan for Gout - New Gout Drugs - Pegloticase Continues Its Hopeful PathMay 2008 the U.S. causes, symptoms and home remedies Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.
Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels.
Pegloticase is Getting Closer to an Application for Approval by the U.SFDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009. We have used a mixture of seriousness and jokes in this composition on Normal Uric Acid Levels. This is to liven the mood when reading about Normal Uric Acid Levels.
May Was a Good Month for Gout SufferersFebuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union. Keeping to the point is very important when writing. So we have to stuck to Treat Gout, and have not wandered much from it to enhance understanding.
- 31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial.
- It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least.
Other patient groups know the best way to get rid of joint pain gout causes and symptoms and treatment for gout and arthritis tophi reduction. Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers. To err is human, to forgive is divine. So we would indeed deem you to be divine if you forgive us for any misunderstandings that may arise in this article on Uric Acid Levels.
Has Been Having a Decent Degree of Success<strong>Elimination of gout attacks </strong>In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial. It is always better to use simple English when writing descriptive articles, like this one on Normal Uric Acid. It is the layman who may read such articles, and if he can't understand it, what is the point of writing it?
<strong>HOW PEGLOTICASE WORKS </strong> What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove. Interesting is what we had aimed to make this article on Uric Acid Levels. It is up to you to decide if we have succeeded in our mission!
- The world of natural gout remedies, uric acid's removal can be improved by making it more soluble.
- This is achieved by drinking lots of water and by raising body pH levels in various ways.
- Time and tide waits for no man.
- So once we got an idea for writing on Gout Sufferer, we decided not to waste time, but to get down to writing about it immediately!
<strong>SIDE EFFECTS </strong> Of course Pegloticase has caused side effects, in the extension trial in about 1 in 5 patients. The developing company has said that most were mild, moderate, or controllable. But in some cases more severe side effects have been described as including chest and back pains, muscle cramps, sweating and flushes. We have used clear and concise words in this article on Gout Remedies to avoid any misunderstandings and confusions that can be caused due to difficult words.
Pegloticase's answer to the foods that lower uric acid levels problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase. As the information we produce in our writing on Gout may be utilized by the reader for informative purposes, it is very important that the information we provide be true. We have indeed maintained this. .
This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones how does fluid intake cause, affect, and help cure gout?.